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自从1954年McCuistion等报告了第一例新生儿LE样皮肤损害后,一般认为新生儿LE有盘状损害是一个良性疾患。它有以下诸特征:①盘状LE样损害在出生时或生后不久出现,②组织学发现符合LE,③损害可存在几个月,但一般在一岁内消失,仅遗留萎缩、毛细血管扩张或色素改变。损害可不治而愈,④抗核抗体或LE试验可阳性,但在几个月内转阴,⑤可出现贫血、肝肿大或脾肿大等全身症状,⑥母亲有活动性或潜伏性结缔组织病。
Since the first case of neonatal LE-like skin lesions was reported by McCuistion et al. In 1954, it is generally accepted that there is a placental damage in the neonatal LE as a benign condition. It has the following characteristics: ① disc-like LE-like lesions occur at birth or shortly after birth, ② histological findings consistent with LE, ③ damage can exist for a few months, but generally disappear within one year, leaving only atrophy, capillaries Dilatation or color change. Damage can be cured, ④ anti-nuclear antibodies or LE test can be positive, but negative in a few months, ⑤ may occur anemia, hepatomegaly or splenomegaly and other systemic symptoms, ⑥ mothers with active or latent connective Tissue disease.