论文部分内容阅读
降钙素是调节钙磷代谢的主要激素之一，天然降钙素及其合成类型物目前在临床上用于治疗老年性骨质疏松、Ｐａｇｅｔｅ＇ｓ症等。本文主要综述了降钙素的构效关系研究进展，并从其二级结构方面对影响其降钙活性的因素进行了阐明。
Calcitonin is one of the main hormones that regulate calcium and phosphorus metabolism. Natural calcitonin and its synthetic types are currently used clinically to treat senile osteoporosis, Pagete’s disease and the like. This review summarizes the research progress of the structure-activity relationship of calcitonin, and elucidates the factors affecting the activity of calcitonin from its secondary structure.