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哌拉西林是第三代青霉素类药物,除有一般抗菌作用外,主要对铜绿假单胞菌有效,其作用强于羟苄西林和磺苄西林,临床应用广泛。它所以选择三唑巴坦为其配伍药,主要有以下原因:三唑巴坦与舒巴坦和克拉维酸一样,均为不可逆型的β-内酰胺抑制药,如果遇到细菌所长生的β-内酰酶,它们首先与其作用而保护其配伍的药物免受破坏,与舒巴坦和克拉维酸相比,三唑巴坦对各种细菌产生的酶的作用最强,而且三
Piperacillin is the third generation of penicillins, in addition to the general antibacterial effect, the main Pseudomonas aeruginosa effective, its role is stronger than that of ampicillin and benzyl amoxicillin, a wide range of clinical applications. So it is the choice of tazobactam for its compatibility with drugs, mainly for the following reasons: Tazobactam and sulbactam and clavulanic acid, are irreversible β-lactam inhibitors, in case of bacterial growth β -lactamases, which first function with them to protect their compatible drugs from destruction, compared to sulbactam and clavulanic acid, tazobactam for the strongest effect on the enzymes produced by various bacteria, and tris