高泌乳素血症已证实不是一种稀发的疾病,许多病例来自垂体肿瘤——泌乳素瘤。为确定成年妇女血清泌乳素浓度的正常和病理范围,作者做了4199名妇女的泌乳素测定。对象是1979～1990年以不孕、月经紊乱、多毛或溢乳就诊的14～43岁的病人。服药、甲状腺机能减退或有全身性疾病者及CT扫描蝶鞍区空虚的除外。研究对象分五组:A组753名月经正常无明显内分泌异常的以不孕 Hyperprolactinemia has not been shown to be a rare disease. Many cases come from the pituitary tumor, prolactinoma. To determine the normal and pathological range of serum prolactin concentrations in adult women, the authors measured prolactin in 4199 women. Subjects were 14 to 43 year-old patients who presented with infertility, menstrual disorders, hirsutism, or galactorrhea from 1979 to 1990. Patients taking medications, hypothyroidism, or systemic diseases, and CT scans in the sella area were excluded. The subjects were divided into five groups: 753 men in group A with infertility without normal endocrine abnormalities