门脉高压性胃病(PHG)是上消化道出血的常见原因之一。目前已公认引起出血的原因是胃黏膜屏障损伤。以往单纯采用药物降低门脉压治疗但效果欠佳。作者近几年来应用洛赛克或雷尼替丁联合心得安长期口服治疗和预防门脉高压性胃病及出血,并与单用心得安比较,观察其疗效。报告如下。 Portal hypertensive gastropathy (PHG) is one of the common causes of upper gastrointestinal bleeding. Has been recognized as the cause of bleeding is gastric mucosal barrier injury. In the past simply using drugs to reduce portal pressure treatment but the effect is not good. In recent years, the authors applied Losec or ranitidine combined with propranolol for long-term oral treatment and prevention of portal hypertensive gastropathy and bleeding, and compared with propranolol alone to observe its efficacy. The report is as follows.