成纤维细胞生长因子(Fibroblast Growth Factor,FGF)是一组体内分布广泛的具有生长因子活性的多肽,由机体组织自身合成,通过与靶细胞膜表面的特异性受体结合,调节细胞的生长和分化,因能明显地促进成纤维细胞的有丝分裂作用,故而称为成纤维细胞生长因子,又因和肝素有很高的亲和力,故而又称为肝素结合生长因子(Heparin binding growth factor)。目前发现FGF至少有20个成员,它们有很高的序列同源性,结构上都有一个保 Fibroblast growth factor (FGF) is a group of widely distributed in the body with growth factor activity of the peptide by the body’s own tissue synthesis, through the membrane with the target cell-specific receptors to regulate cell growth and differentiation , Because it can significantly promote the mitosis of fibroblasts, so called fibroblast growth factor, because of its high affinity with heparin, it is also known as Heparin binding growth factor (Heparin binding growth factor). At present, there are at least 20 members of FGF, which have high sequence homology and have a structural protection