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目的:了解长春市新生儿脐血血铅含量及其对听力的影响。方法:对690例新生儿脐血样本在严格质量控制下用Z/3030型石墨炉原子吸收分光光度计进行血铅测定,于生后2～3天进行耳声发射听力筛查(OAE)来评价神经是否受损。结果:690例新生儿脐血血铅水平成正态分布,范围6～78μg/L,均值33.32μg/L,标准差18.078μg/L。以血铅≥60μg/L为相对高铅组72例,血铅<60μg/L为相对低铅组618例,两组OAE2～3天初筛阳性率比较差异有统计学意义(P<0.05)。结论:长春市新生儿脐血血铅水平为(33.32±18.078)μg/L,但低血铅水平仍可引起听神经损伤。
Objective: To understand the blood lead levels of neonatal cord blood and their effects on hearing in Changchun City. Methods: 690 neonatal umbilical blood samples were tested for blood lead level with Z / 3030 graphite furnace atomic absorption spectrophotometer under strict quality control. OAE was performed 2 to 3 days after birth Evaluate whether the nerve is damaged. Results: The blood lead levels of 690 newborn infants were normal distribution with the range of 6 ~ 78μg / L, with a mean of 33.32μg / L and a standard deviation of 18.078μg / L. There were 72 cases of blood lead≥60μg / L in relative high lead group, 618 cases of blood lead <60μg / L in low lead group, and there was significant difference in positive rate of OAE2 ~ 3 days between two groups (P <0.05) . Conclusion: The level of blood lead in neonatal umbilical blood of Changchun City was (33.32 ± 18.078) μg / L, but the level of low blood lead still could cause the injury of auditory nerve.