将溴氰菊酯及其拮抗剂舒筋灵微量注入家兔侧脑室、第三脑室、第四脑室和脊髓蛛网膜下腔,比较了各部位染毒的毒性症状、发作时间及舒筋灵的拮抗效果。实验结果表明,溴氰菊酯对中枢多部位神经元均有毒作用,脑是其毒作用的主要部位,部分运动症状与溴氰菊酯对脊髓神经元的毒作用有关。舒筋灵能部分拮抗这种毒作用,其拮抗作用的机制可能是抑制了注射部位周围局部神经元的异常兴奋。 Deltamethrin and its antagonist Shujin were injected into the lateral ventricle, the third ventricle, the fourth ventricle and the spinal subarachnoid space of rabbits respectively. The toxicity symptoms, the onset time, Antagonistic effect. The experimental results show that deltamethrin exerts a toxic effect on the neurons in the central part of the brain. The brain is the main part of the neurotoxicity. Some of the motor symptoms are related to the toxic effects of deltamethrin on the spinal cord neurons. Shujin Ling can partially antagonize this toxic effect, the mechanism of its antagonistic effect may be inhibited injection of local neurons around the abnormal excitement.