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目的 探索不同饮水类型与结直肠癌发病率之间的关系。方法 随机抽取了浙江省海宁市的 8个乡镇为研究区 ,应用回顾前瞻性研究方法 ,分别对不同饮水类型的结肠、直肠癌发病率进行分析并作相对危险度 (RR)估计。结果 饮用井水、自来水、河水和池塘水者的结直肠癌发病率男性分别为 3 .19/ 10万、7.99/ 10万、45 .0 6 / 10万和 12 6 .0 4/ 10万 ;女性分别为 3 .0 6 / 10万、5 .17/ 10万、6 3 .43/ 10万和 81.76 / 10万 ,均呈依次递增趋势 (P <0 .0 1)。RR分析显示 ,饮用池塘水、河水者 ,罹患结直肠癌的危险性分别达到 14.13和 39.5 1(男性 )以及 2 0 .73和 2 6 .72 (女性 )。结论 不同饮水类型的结直肠癌发病率有差异 ,饮用池塘水、河水与结直肠癌发病有关
Objective To explore the relationship between different drinking water types and the incidence of colorectal cancer. Methods Eight townships in Haining City, Zhejiang Province were randomly selected as the study area. Retrospective prospective research methods were applied to analyze the incidence of colon and rectal cancer in different drinking water types and estimate the relative risk (RR). Results The incidence of colorectal cancer in drinking well water, tap water, river water, and pond water was 3.9/100,000, 7.99/100,000, 45.06/100,000 and 126.4/100,000 respectively. Women were 3.06/100,000, 5.7/100,000, 63.43/100,000, and 81.76/100,000, respectively, both of which showed an increasing trend (P < 0.01). RR analysis showed that the risk of developing colorectal cancer was 14.13 and 39.5 1 (male) and 20.73 and 26.72 (female), respectively, in drinking pond water and river water. Conclusion The incidence of colorectal cancer is different in different types of drinking water. Drinking pond water, river water and the incidence of colorectal cancer are related.