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目的:观察超早期溶栓脑梗死患者联合补气通滞汤及血必净注射液治疗对炎性因子变化的影响。方法:选取本院106例行超早期溶栓脑梗死患者为研究对象,随机分为观察组与对照组,2组均为53例,观察组采取补气通滞汤联合血必净注射液治疗,对照组仅采取血必净注射液治疗,比较2组炎性因子改变。结果:治疗后2组炎性因子水平均明显下降,与治疗前比较显著较低(P<0.05),治疗后观察组白细胞介素-8(IL-8)、白细胞介素-6(IL-6)、肿瘤坏死因子-α(TNF-α)、C-反应蛋白(CRP)显著低于对照组(P<0.05)。结论:超早期溶栓脑梗死患者联合补气通滞汤血必净注射液治疗效果显著,可降低炎性因子水平,具有较高的临床应用价值。
Objective: To observe the effects of combination of Buqi Tongji Decoction and Xuebijing injection on the changes of inflammatory factors in patients with ultra-early thrombolytic cerebral infarction. Methods: A total of 106 patients with ultra-early thrombolytic cerebral infarction in our hospital were selected as study subjects and randomly divided into observation group and control group, with 53 cases in both groups. The observation group was treated with Buqi Tongzhu Decoction combined with Xuebijing injection , The control group was treated with Xuebijing Injection only, and the changes of inflammatory cytokines in the two groups were compared. Results: The levels of inflammatory cytokines in two groups were significantly decreased after treatment, which were significantly lower than those before treatment (P <0.05). After treatment, the levels of IL-8, IL- 6), tumor necrosis factor-α (TNF-α) and C-reactive protein (CRP) were significantly lower than those in the control group (P <0.05). Conclusion: Ultra-early thrombolytic cerebral infarction combined with qi qi stagnation soup Xuebijing Injection treatment effect is significant, can reduce the level of inflammatory cytokines, with high clinical value.