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神经母细胞瘤的形态学和分子细胞遗传学染色体ＩＰ缺失、致癌基因ＭＹＣＮ增殖和倍体变异已被证明和神经母细胞瘤预后有关，本文报道１４例神经母细胞瘤用荧光原位杂交（ＦＩＳＨ）和Ｓｏｕｔｈｅｒｎ印迹法来评估染色体核型变化和ＭＹＣＮ基因的复制。结果：从２０例未经...
Neuroblastoma morphology and molecular cytogenetics Chromosome IP deletion, oncogene MYCN proliferation and ploidy variation have been shown to be associated with the prognosis of neuroblastoma. In this paper, 14 cases of neuroblastoma were detected by fluorescence in situ hybridization (FISH ) And Southern blotting to assess chromosomal karyotyping and MYCN gene replication. Results: From 20 cases without ...