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经皮球囊血管扩张术及血管内支架置入术是近年来兴起的一种治疗方法,可避免外科手术的创伤大,并发症多,死亡率高等缺点。但其术后再狭窄或闭塞的发生率较高,一年内达30％,因而限制了该技术的临床应用和发展[1]。实验旨在探讨局部转导血管内皮细胞生长因子（VEGF）基因促进支架及血管损伤处的内皮形成,及其在防治再狭窄发生中的作用。 一、材料与方法
Percutaneous balloon dilation and endovascular stenting are emerging as a treatment method in recent years, which can avoid the disadvantages of surgical trauma, multiple complications and high mortality. However, the incidence of postoperative restenosis or occlusion is high, reaching 30% within one year, thus limiting the clinical application and development of this technique [1]. The aim of this experiment is to investigate the role of locally transduced vascular endothelial cell growth factor (VEGF) gene in promoting endothelial and endothelial formation at scaffolds and vascular lesions and its role in the prevention and treatment of restenosis. First, materials and methods