糖尿病患者的一个重要病理标志是高血糖,糖化血红蛋白(HbA1c)水平是糖尿病程度以及治疗过程中血糖控制的衡量标准[1]。HbA1c水平每降低一个百分点,与糖尿病相关危险事件的危险性呈现降低状态,如病死率、并发心肌梗塞及微血管并发症的发生率等[2]。HbA1c水平的控制是否适当直接关系到糖尿病患者的治疗效果及预后[3]。本文报道口服降糖药控制不佳的2型糖尿病患者不同HbA1c水平与胰岛β细胞功能及胰岛素抵抗指数 An important pathological hallmark of patients with diabetes is hyperglycemia. HbAlc levels are a measure of the severity of diabetes and glycemic control during treatment [1]. For each 1% reduction in HbA1c levels, there is a reduced risk of diabetes-related risk events such as mortality, concurrent myocardial infarction, and microvascular complications [2]. The appropriate level of HbA1c control is directly related to the therapeutic effect and prognosis of diabetic patients [3]. This article reports the poor control of patients with oral hypoglycemic type 2 diabetes HbA1c levels and pancreatic β-cell function and insulin resistance index