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研究鹅绒藤对小鼠免疫功能的影响和体外抗菌活性。方法用鹅绒藤浸膏(AECC)及其正丁醇提取物(BECC)给实验小鼠灌胃后测定细胞免疫及体液免疫指标。用K—B法做了AECC的药敏试验。结果(1)AECC对小鼠免疫功能无明显影响,BECC在高剂量下(3g/kg·d-1)能增加耳反应程度指数(P<0.05)和胸腺重量(P<0.05),减少巨噬细胞吞噬率和吞噬指数(P<0.01)。在低剂量下(1.5g/kg·d-1)只能增加耳反应程度指数(P<0.05);(2)AECC在各种浓度下无抑菌圈。结论BECC能增强小鼠细胞免疫功能,AECC在体外无抗菌活性。
To study the effect of goose down vine on immune function and antibacterial activity in vitro. METHODS: Cellular immunity and humoral immunity were measured after intragastric administration of AECC and BECC to mice. The ABC susceptibility test was performed using the K-B method. Results (1) AECC had no effect on the immune function of mice. BECC increased ear response index (P<0.05) and thymus weight at high dose (3g/kg·d-1) (P<0.05). ), Decrease macrophages phagocytosis rate and phagocytic index (P <0.01). At the low dose (1.5g/kg d-1), the ear response index only increased (P<0.05); (2) AECC had no inhibition zone at various concentrations. Conclusion BECC can enhance the cellular immune function of mice. AECC has no antibacterial activity in vitro.