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目的分析多潘立酮联合阿米替林治疗功能性消化不良的效果。方法资料选取本院2014年8月至2016年8月治疗的105例功能性消化不良患者予以回顾性分析,根据治疗时不同方案将其分为对照组(45例)与研究组(60例),前者单纯给予多潘立酮治疗,后者联合阿米替林治疗,比较两组治疗前后临床症状改善情况及不良反应发生率。结果两组治疗后临床症状评分均较治疗前降低,且研究组降低幅度大于对照组,比较差异均具有统计学意义(P<0.05);研究组不良反应总发生率8.27%低于对照组22.22%,比较差异具有统计学意义(P<0.05)。结论功能性消化不良行多潘立酮联合阿米替林治疗可取得良好效果,不仅可改善患者临床症状,而且安全性高,具临床推广价值。
Objective To analyze the effect of domperidone combined with amitriptyline in the treatment of functional dyspepsia. METHODS: A total of 105 patients with functional dyspepsia treated in our hospital from August 2014 to August 2016 were retrospectively analyzed. According to the different treatment plans, they were divided into control group (45 cases) and study group (60 cases) , The former was given only domperidone treatment, the latter combined with amitriptyline treatment, the clinical symptoms of both groups before and after treatment to improve the situation and the incidence of adverse reactions. Results The scores of clinical symptoms in both groups were lower than those before treatment, and the reduction rate in the study group was larger than that in the control group (P <0.05). The overall incidence of adverse reactions in the study group was 8.27% lower than that in the control group %, The difference was statistically significant (P <0.05). Conclusion The treatment of dyspepsia with domperidone combined with amitriptyline can achieve good results. It can not only improve the clinical symptoms but also have high safety and clinical value.