IL-16基因-295T〉C多态性与肾透明细胞癌易感性的相关性研究

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目的研究中国南方汉族人群中白细胞介素-16(IL_16)基因一295T〉C多态性与肾透明细胞癌(CCRCC)易感性的相关性。方法采用以医院为基础的病例对照研究模式,通过面访填写调查表并采用聚合酶链反应一限制性片段长度多态性(P(、R—RFI.P)方法检测年龄和性别匹配的中国南方汉族300例患者和300例正常人群的IL-16gene-295T〉C基因型。并采用分层分析进一步探讨与罹患CCRCC相关的可能因素。结果与TT型携带者相比,CT型(OR=0.78,95%CI=0.55~1.09)或CC型(0.37,
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