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目的:分析青海地区儿童紫癜性肾炎的临床相关因素,指导临床治疗及预后的评估。方法:对我院2004年7月—2009年6月收治的256例过敏性紫癜病人资料进行分析。结果:256例过敏性紫癜患儿中有效病例共221例。紫癜性肾炎共109例,非肾炎共112例。肾炎组男60例,女49例,平均年龄(7.6±1.8)岁。肾炎组皮疹持续天数(18.5±4.5)天,血小板计数范围在(312±109)×109/L。非肾炎组男59例,女53例,平均年龄(8.1±1.7)岁。皮疹持续天数(9.8±2.3)天,血小板计数范围在(221±71)×109/L。221例病人中皮疹反复出现3次以上的占30例,有消化道出血的患儿85例。结论:青海地区紫癜性肾炎的发生率为42%。紫癜性肾炎的发生与皮疹持续时间长短,皮疹反复出现的次数,消化道出血及血小板值有明确的相关性。
Objective: To analyze the clinically relevant factors of purpura nephritis in children in Qinghai Province, and to guide the evaluation of clinical treatment and prognosis. Methods: The data of 256 patients with allergic purpura admitted to our hospital from July 2004 to June 2009 were analyzed. Results: A total of 221 valid cases of 256 cases of Henoch-Schonlein purpura in children. A total of 109 cases of purpura nephritis, non nephritis in 112 cases. Nephritis group 60 males and 49 females, mean age (7.6 ± 1.8) years old. Nephritis rash continued for days (18.5 ± 4.5) days, platelet count range (312 ± 109) × 109 / L. Non-nephritis group of 59 males and 53 females, mean age (8.1 ± 1.7) years. Rash continued for days (9.8 ± 2.3) days with a platelet count range of (221 ± 71) × 109 / L. 221 cases of patients with rash repeated more than 3 times in 30 cases, 85 cases of children with gastrointestinal bleeding. Conclusion: The incidence of purpura nephritis in Qinghai Province was 42%. The occurrence of purpura nephritis and rash duration, the number of repeated rashes, gastrointestinal bleeding and platelet values have a clear correlation.