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目的观察泛昔洛韦联合窄谱UVB治疗带状疱疹的疗效。方法 56例患者随机分为治疗组和对照组。治疗组30例:泛昔洛韦片250mg,3次/d,口服,同时采用窄谱UVB照射,隔日1次。对照组26例:仅给予泛昔洛韦片口服。结果治疗组有效率为88.9%,对照组有效率为68.5%,且治疗组在止疱时间、结痂时间、止痛时间上均明显优于对照组。两组差异有统计学意义(P<0.05)。结论泛昔洛韦联合窄谱UVB治疗带状疱疹的疗效满意,可降低带状疱疹后遗神经痛的发生率,值得临床应用。
Objective To observe the efficacy of famciclovir combined with narrow-band UVB in the treatment of shingles. Methods 56 patients were randomly divided into treatment group and control group. Treatment group 30 patients: famciclovir 250mg, 3 times / d, orally, while using narrow-band UVB irradiation, every other day. Control group, 26 cases: only given famciclovir tablets orally. Results The effective rate was 88.9% in the treatment group and 68.5% in the control group, and the treatment group was significantly better than the control group in blistering time, scabbing time and analgesic time. The difference between the two groups was statistically significant (P <0.05). Conclusion Famciclovir combined with narrow-band UVB treatment of shingles with satisfactory results can reduce the incidence of postherpetic neuralgia, is worth clinical application.