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应用自由基清除剂维生素Ｅ（ＶＥ）、维生素Ｃ（ＶＣ）联合佐治新生儿缺氧缺血性脑病（ＨＩＥ），观察其疗效和治疗前后患儿血清中脂质过氧化物（ＬＰＯ）和超氧化物歧化酶（ＳＯＤ）含量的变化，并同时与对照组比较。其结果显示：治疗组的显效率高于对照组（Ｐ＜０．０５）；在治前，两组血清ＳＯＤ与ＬＰＯ含量比较均无差异（Ｐ＜０．０５），在治后，治疗组ＳＯＤ明显增加，ＬＰＯ明显降低，与对照组比较均有显著性差异（Ｐ＜０．００１）。
Free radical scavenger vitamin E (VE) and vitamin C (VC) were used in combination with neonatal hypoxic-ischemic encephalopathy (HIE) to observe their curative effect and the changes of serum lipid peroxides (LPO) Oxide dismutase (SOD) content changes, and at the same time with the control group. The results showed that: the effective rate of the treatment group was higher than that of the control group (P <0.05); before treatment, there was no significant difference in the serum SOD and LPO content between the two groups (P <0.05) SOD increased significantly, LPO decreased significantly compared with the control group (P <0.001).