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CD11c/CD18是主要分布于髓样细胞表面的一种跨膜糖蛋白,属于β2整合素家族。它既是纤维蛋白原、脂多糖和iC3b的受体,又可介导髓样细胞与其它细胞、底物的粘附,参与机体的免疫炎性反应及细胞的分化增殖。
CD11c / CD18 is a transmembrane glycoprotein mainly distributed on the surface of myeloid cells and belongs to the β2 integrin family. It is not only fibrinogen, lipopolysaccharide and iC3b receptors, but also mediate myeloid cells and other cells and substrates adhesion, involved in the body’s immune inflammatory reaction and cell differentiation and proliferation.