作者对妊娠18周前发生风疹感染的18例孕妇,在妊娠20～26周期间,通过超声波导向穿刺,直接获取其纯胎血1～2ml,用免疫分析测定风疹特异性 IgM,以此作为先天性风疹的产前诊断。18例孕妇均确诊为风疹感染。其中14例有临床和血清学证据,她们在妊娠初或妊娠 18 pregnant women 18 weeks before pregnancy, rubella infection in 18 pregnant women, during pregnancy 20 to 26 weeks, guided by ultrasound-guided direct access to its pure fetal blood 1 ~ 2ml, immunohistochemical determination of rubella-specific IgM as a precursor to Prenatal diagnosis of sexual rubella. 18 pregnant women were diagnosed as rubella infection. Fourteen of them had clinical and serological evidence of early pregnancy or pregnancy