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目的:分析腹腔镜手术联合药物治疗子宫内膜异位症伴不孕的临床疗效。方法:将收治的126例子宫内膜异位症伴不孕患者作为研究对象,遵照知情同意原则并按照随机数字表法分为两组,对照组62例采用腹腔镜手术治疗,观察组64例在对照组的基础上加用孕三烯酮治疗,比较分析两组的临床疗效。结果:观察组的总有效率为98.4%,对照组为87.1%,组间差异有统计学意义(P<0.05);两组患者治疗前血清CA125差异无统计学意义,治疗后两组患者的血清CA125均明显降低,分别与本组治疗前比较差异有统计学意义(P<0.05),组间差异无统计学意义(P>0.05);观察组的不良反应发生率为3.1%,对照组为8.1%,组间差异无统计学意义(P>0.05);观察组的妊娠率为29.7%,对照组为16.1%,组间差异有统计学意义(P<0.05)。结论:腹腔镜手术联合药物治疗子宫内膜异位症伴不孕临床疗效满意,明显优于单独的手术治疗且安全性可靠,是临床首选的治疗方案之一。
Objective: To analyze the clinical efficacy of laparoscopic surgery combined with drug treatment of endometriosis with infertility. Methods: 126 cases of endometriosis with infertility patients were treated as subjects, according to the principle of informed consent and random number table divided into two groups, the control group of 62 patients treated by laparoscopy, the observation group of 64 cases On the basis of the control group plus gestrinone treatment, comparative analysis of the clinical efficacy of the two groups. Results: The total effective rate was 98.4% in the observation group and 87.1% in the control group, with significant difference between the two groups (P <0.05). There was no significant difference in serum CA125 between the two groups before treatment (P <0.05). There was no significant difference between the two groups (P> 0.05). The incidence of adverse reactions in the observation group was 3.1%, while that in the control group Was 8.1%. There was no significant difference between the two groups (P> 0.05). The pregnancy rate was 29.7% in the observation group and 16.1% in the control group. There was significant difference between the two groups (P <0.05). Conclusion: Laparoscopic surgery combined with drug treatment of endometriosis with infertility clinical efficacy was significantly better than the separate surgical treatment and reliable, is one of the preferred clinical treatment options.