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小柴胡汤出于《伤寒论》,由柴胡、人参、黄芩生姜、大枣、甘草、半夏组成,是著名的和解少阳方。近年来,国外特别是日本对其药理和临床应用研究颇多。药理研究一、抑制血小板聚集和前列腺素合成:Sakae Amagaya等研究了小柴胡汤对胶原诱发血小板聚集的抑制时间过程和对前列腺素生物合成的抑制作用。给一次性静注胶原后的正常小鼠口服小柴胡汤(1.1g/kg),口服后1和5h的胶原诱发血小板聚集的抑制率分别为53％和68％。体外实验小柴胡汤
Xiao Chai Hu Tang is based on the “Treatise on Febrile Diseases.” It is composed of Bupleurum, Ginseng, Huangqi Ginger, Jujube, Licorice and Pinellia. It is a famous reconciliation Shaoyang Party. In recent years, foreign countries, especially Japan, have studied a lot of their pharmacological and clinical applications. Pharmacological studies 1. Inhibition of platelet aggregation and prostaglandin synthesis: Sakae Amagaya et al studied the inhibition of collagen-induced platelet aggregation by Xiao Chai Hu Tang and the inhibition of prostaglandin biosynthesis. Oral Xiaochaihu Decoction (1.1g/kg) was administered to normal mice after one-time intravenous injection of collagen. The inhibitory rate of collagen-induced platelet aggregation at 1 and 5 hours after oral administration was 53% and 68%, respectively. In vitro experiment Xiao Chai Hu Tang