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乙胺碘呋酮(Amiodarone)在临床广泛应用,其副作用也日益增多。我院自1982年以来,应用该药治疗113例各种心律失常病人,系统观察了在心血管方面的副作用。现报道如下。对象和方法一、病例选择 113例中男71例,女42例。年龄5～80岁(平均57.2岁)。60岁以上48例(42.4％)。专科门诊24例,住院患者89例。冠心病62例,高血压性心脏病6例,风湿性瓣膜病8例,心肌炎18例,心肌病4例,先天性心脏病2例,预激综合征2例,原因不明11例。病史2月～40年不等。心功能不全史者36例(31.7％)。心律失常类型:持续性房颤19例,阵发性房颤或房扑28例,房颤伴Ⅱ度房
Amiodarone is widely used clinically and its side effects are increasing. Our hospital since 1982, the application of the drug treatment of 113 cases of various arrhythmia patients, the systematic observation of the cardiovascular side effects. Report as follows now. Subjects and methods A case selection 113 cases of male 71 cases, 42 females. Age 5 to 80 years (mean 57.2 years old). 48 cases over the age of 60 (42.4%). Specialist outpatient 24 cases, hospitalized patients 89 cases. 62 cases of coronary heart disease, hypertensive heart disease in 6 cases, rheumatic valvular disease in 8 cases, myocarditis in 18 cases, 4 cases of cardiomyopathy, congenital heart disease in 2 cases, 2 cases of pre-excitation syndrome, unexplained 11 cases. Medical history from February to 40 years. 36 cases of heart failure history (31.7%). Arrhythmia type: persistent atrial fibrillation in 19 cases, paroxysmal atrial fibrillation or atrial flutter in 28 cases, atrial fibrillation with Ⅱ degree room