原发性肝胆管结石可反复引起胆道梗阻和感染,造成肝功能损害,出现胆汁性肝硬化而最后死于肝肾功能衰竭.因此,提高原发性肝胆管结石的治愈率,减少并发症是经常面临的课题。中医认为,胆道疾患多有脾阴虚佐证,故主张“胆脾并治”,在治疗中注重调理脾胃扶正养阴。我们根据中医胆脾并治理论,设计出清胆护肝汤Ⅲ号,并就这一方剂对梗阻性黄疸大鼠肝脏组织化学成分的影响进行了实验观察,以探讨其疗效和作用机理。1 材料和方法 Primary hepatolithiasis can repeatedly cause biliary obstruction and infection, resulting in liver damage, biliary cirrhosis, and finally death in liver and kidney failure. Therefore, to improve the cure rate of primary hepatobiliary stones, reduce complications Frequently faced issues. Chinese medicine believes that biliary tract disorders are mostly evidenced by spleen yin deficiency, so they advocate “stomach and spleen.” In treatment, they pay attention to modulating the spleen and stomach to support yang. According to the theory of treating sputum and spleen, we designed Qingdan Hugan Decoction No. III and observed the effect of this prescription on the hepatic histochemical composition of rats with obstructive jaundice to observe its efficacy and mechanism of action. 1 Materials and methods