在应激性溃疡形成过程中,中枢单胺类神经递质的代谢加快。去甲肾上腺素、多巴胺、γ-氨基丁酸、5-羟色胺和乙酰胆碱都可能参与应激性渍疡形成。脑内注射一些神经肽也有预防或加重应激性溃疡发生的作用。下丘脑外侧区、杏仁复合体以及与其联系的其他脑区的神经通路,亦与应激性溃疡的形成有关。 During the formation of stress ulcer, central monoamine neurotransmitter metabolism accelerated. Norepinephrine, dopamine, γ-aminobutyric acid, serotonin, and acetylcholine may be involved in the formation of stress ulcer. Intracerebral injection of some neuropeptides also prevent or aggravate the occurrence of stress ulcer. The hypothalamic lateral zone, the almond complex, and the brain pathways associated with it, are also involved in the formation of stress ulcers.