雌激素是一种类固醇性激素,对中枢神经系统具有重要的作用。近年来发现,阿尔茨海默氏病、帕金森氏病、缺血性脑卒中都与雌激素缺乏存在一定关系,并且存在性别差异。本文针对雌激素受体分类、作用,以及对脑缺血损伤的影响展开论述,旨在为雌激素药物治疗提供理论依据。 Estrogen is a steroid hormone that plays an important role in the central nervous system. In recent years, Alzheimer’s disease, Parkinson’s disease and ischemic stroke have been found to have a certain relationship with estrogen deficiency, and there are gender differences. In this paper, estrogen receptor classification, role, as well as the impact of cerebral ischemia injury were discussed in order to provide a theoretical basis for estrogen drug therapy.