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目的:研究肋骨血管肉瘤的临床病理特征、治疗及转归。方法:对1例原发性肋骨血管肉瘤的组织病理学、免疫组化结果进行观察分析,结合文献进行讨论。结果:本例血管肉瘤组织学表现为肿瘤细胞呈梭形或上皮样细胞形态。免疫组化染色表达CD31、CD34。结论:肋骨原发性血管肉瘤极少见,结合组织学形态并联合应用多项血管内皮标记物可作出明确诊断。早期发现、局部手术切除和结合术后放化疗有助于延长患者生存期。
Objective: To study the clinicopathological features, treatment and prognosis of rib angiosarcoma. Methods: One case of primary rib angiosarcoma histopathology, immunohistochemistry results were observed and analyzed, combined with the literature to discuss. Results: The histological appearance of angiosarcoma in this case was spindle or epithelioid cell morphology. Immunohistochemical staining of CD31, CD34. CONCLUSIONS: Primary angiosarcomas of the ribs are extremely rare and can be clearly diagnosed in combination with histological findings and with multiple vascular endothelial markers. Early detection, partial surgical resection combined with postoperative radiotherapy and chemotherapy help to prolong the survival of patients.