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目的探讨慢性胃病患者T细胞亚群、一氧化氮(NO)、氨基己糖含量变化与Hp感染的关系.方法分别对30例慢性胃炎(CG)、32例消化性溃疡合并慢性胃炎(PU+CG)与20例正常对照分别进行T细胞亚群、NO、氨基己糖含量检测.结果CG患者外周血CD+3,CD+4,CD+8,CD+4/CD+8(607%±24%,358%±25%,252%±24%,143±015)分别较正常对照组(683%±39%,430%±38%,264%±17%,164±018)明显降低(P<005~001);其Hp+组CD+3,CD+4(597%±25%,348%±26%)较Hp-组(622%±09%,369%±20%)为低(P<001,005);重度CG患者71%有Hp感染,其CD+3,CD+4,CD+4/CD+8(595%±21%,354%±27%,140±013)分别均较轻中度患者(623%±17%,374%±18%,150±013)明显减低(P<005~001).CG和PU+CG患者Hp感染率分别为600%和750%,其氨基己糖含量(mg/g,40?
Objective To investigate the relationship between changes of T cell subsets, nitric oxide (NO) and hexose hexose contents in chronic gastritis patients and Hp infection. Methods T cell subsets, NO and hexosamine contents were measured in 30 cases of chronic gastritis (CG), 32 cases of peptic ulcer complicated with chronic gastritis (PU + CG) and 20 cases of normal control respectively. Results The levels of CD + 3, CD + 4, CD + 8 and CD + 4 / CD + 8 in peripheral blood of CG patients were significantly higher than those of CG patients 15) were significantly lower than the normal control group (683% ± 39%, 430% ± 38%, 264% ± 17%, 164 ± 018) P <005 ~ 001). Compared with Hp-group (622% ± 00), CD + 3 and CD + 4 in Hp + group were significantly higher than those in Hp group (597% ± 25%, 348% ± 26% 71% of severe CG patients had Hp infection. The CD + 3, CD + 4, CD + 4 / CD + 8 (595% ± 9%, 369% ± 20% 21%, 354% ± 27%, 140 ± 013) were respectively mild to moderate (623% ± 17%, 374% ± 18% , 1 50 ± 0 13) Ming Reduction (P <005 ~ 001). Hp infection rates in patients with CG and PU + CG were 60.0% and 75.0%, respectively, and their hexosamine contents (mg / g, 40?