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目的研究环氧合酶-2抑制剂药物的应用状况和发展趋势,为临床合理、有效、经济地选用药物提供科学依据。方法采用金额排序和用药频度(DDDs)、日均费用(DDC)方法,对四川大学华西医院2008年-2010年环氧合酶-2抑制剂药物的临床应用情况进行统计分析。结果 2008年-2010年间,该院环氧合酶-2抑制剂药物的应用数量和销售金额呈逐年上升趋势,其中选择性环氧合酶-2抑制剂药物的用量增幅较大,非选择性环氧合酶-2抑制剂药物用量呈下降趋势。结论该院环氧合酶-2抑制剂药物临床应用合理,选择性环氧合酶-2占主导地位,有较好的发展前景。
Objective To study the application status and development trend of cyclooxygenase-2 inhibitor drugs and provide a scientific basis for the rational, effective and economical selection of drugs. Methods The clinical application of cyclooxygenase-2 inhibitor drugs in Huaxi Hospital of Sichuan University from 2008 to 2010 were statistically analyzed with the method of order of magnitude, DDDs and DDC. Results Between 2008 and 2010, the number and sales of cyclooxygenase-2 inhibitor drugs in this hospital increased year by year. The dosage of selective cyclooxygenase-2 inhibitor drugs increased greatly and non-selectivity Cyclooxygenase-2 inhibitor drug usage showed a downward trend. Conclusion The COX-2 inhibitor is reasonable in clinical application and the selective cyclooxygenase-2 occupies a dominant position with good development prospects.