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胰管细胞癌除了保留胰腺特异的标志外,还常表达胃表面上皮、胃粘液腺,或小肠和大肠吸收细胞或杯状细胞的标志,而胰小管腺泡细胞癌只表达胰腺上皮细胞的标志。作者用粘液组织化学、免疫组织化学和电镜技术研究了107例各种组织学类型的胰腺癌,以探索其组织发生和起源。本文采用AB(pH 2.5)-PAS、HID及PA-ConA粘液组化染色分别染酸性、中性、硫酸化粘液及对胃幽门腺和颈粘液腺细胞特异的中性粘液;并用ABC-过氧化酶免疫组化技术检测下列8种单克隆或多克隆抗体的反应:胰腺上皮细胞抗原的抗体(Du-PAN-2及N-
In addition to retaining pancreatic specific markers, pancreatic ductal cell carcinoma often expresses gastric surface epithelium, gastric mucous glands, or small and large intestine markers that absorb cells or goblet cells, whereas pancreatic acinar cell carcinoma expresses only the hallmarks of pancreatic epithelial cells. . The authors studied 107 cases of various histological types of pancreatic cancer using mucin histochemistry, immunohistochemistry, and electron microscopy to explore histogenesis and origin. In this study, we used AB (pH 2.5)-PAS, HID, and PA-ConA mucin staining to stain acidic, neutral, sulfated mucus, and neutral mucus specific for gastric pyloric and cervical mucinous gland cells; and ABC-peroxidase. Immunohistochemistry detects the following 8 monoclonal or polyclonal antibodies: antibodies to the pancreatic epithelial cell antigen (Du-PAN-2 and N-