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目的:研究血小板指标在稳定型心绞痛(SAP),不稳定型心绞痛(UAP)和急性心肌梗死(AMI)发病中的临床意义。方法:随机选择对照组30例、SAP组28例、UAP组19例、AMI组21例,共98例病人测定血小板计数(PLT)、血小板平均体积(MPV)。统计结果由SAS软件分析。结果:UAP组和AMI组患者的PLT分别为161.84±35.67(×109/L)和137.55±28.19(×109/L),明显低于对照组(P<0.01)。SAP组、UAP组和AMI组患者的MPV分别为8.79±1.86(fl)、9.81±1.47(fl)、10.94±1.73(fl)均不同程度的高于对照组。其中UAP组和AMI组增人更显著(P<0.01)。结论:血小板指标检测对判断SAP、UAP和AMI的发生及预后有一定的临床价值。UAP、AMI的PLT和MPV变化与其病变程度有关。
Objective: To study the clinical significance of platelet indices in the pathogenesis of stable angina pectoris (SAP), unstable angina pectoris (UAP) and acute myocardial infarction (AMI). Methods: 30 cases of control group, 28 cases of SAP group, 19 cases of UAP group and 21 cases of AMI group were randomly selected. A total of 98 patients were measured platelet count (PLT) and mean platelet volume (MPV). The statistical results are analyzed by SAS software. Results: The PLT of UAP group and AMI group were 161.84 ± 35.67 (109 / L) and 137.55 ± 28.19 (109 / L), respectively, which were significantly lower than those of the control group (P <0.01). The MPV of patients in SAP group, UAP group and AMI group were 8.79 ± 1.86 (fl), 9.81 ± 1.47 (fl) and 10.94 ± 1.73 (fl), respectively, which were all higher than those in control group. The UAP group and AMI group increased more significantly (P <0.01). Conclusion: The detection of platelet index has some clinical value in judging the occurrence and prognosis of SAP, UAP and AMI. The changes of PLT and MPV in UAP and AMI were related to the degree of lesion.