新生儿缺氧缺血性脑病(HIE)指的是由于围生期缺氧和缺血导致的颅脑损伤的一种严重疾病,是新生儿窒息常见并发症之一,是导致新生儿急性死亡和各种脑瘫、智力发育不良等慢性神经系统损伤的重要原因之一,其治疗效果对患儿的预后有至关重要的作用,降低该疾病的病死率及中枢神经系统残障的发生,是治疗HIE的最终目的。因此 Neonatal hypoxic-ischemic encephalopathy (HIE) is a serious disease of brain injury due to perinatal hypoxia and ischemia and is one of the most common complications of neonatal asphyxia, resulting in acute neonatal death And a variety of cerebral palsy, mental retardation and other chronic nerve damage one of the important reasons, the treatment effect on the prognosis of children has a crucial role in reducing the mortality of the disease and the occurrence of central nervous system disorders, is the treatment HIE’s ultimate goal. therefore