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研究地奥心血康对大鼠实验性心肌缺血的影响。方法：结扎ｗｉｓｔａｒ大鼠左冠状动脉造成急性心肌缺血，设缺血对照组（生理盐水）、地奥心血康组（地奥心血康０．１０ｇ／ｋｇ），阳性药普萘洛尔组（普萘洛尔０．０１ｇ／ｋｇ），各组均在结扎冠脉１５ｍｉｎ后经十二指肠给药，记录给药前后不同时间胸前多导联心电图（９个点），以ΣＳＴ和ＮＳＴ来反映心肌缺血程度和范围，结扎冠脉３ｈ，摘取心脏，用Ｎ—ＢＴ染色确定心肌梗塞面积。结果：地奥心血康０１０ｇ／ｋｇ在３０、６０、１２０、１８０ｍｉｎ使ΣＳＴ分别下降２４％、２９％、３０％、２７％（与对照组比Ｐ＜０．０１、Ｐ＜０．０５）；使ＮＳＴ降低１６％、１７％、１６％、１７％（与对照组比Ｐ＜０．０１）持续１８０ｍｉｎ，使梗塞面积由对照组的１５１４％降到９．６０％（Ｐ＜０．０５）。结论：地奥心血康可降低大鼠实验性心肌缺血程度和缺血范围，减少梗塞面积。
To study the effect of AoxinXingKang on experimental myocardial ischemia in rats. Methods: Acute myocardial ischemia was induced in the left coronary artery of the wistar rats. Ischemia control group (Physiological saline), DiaoXueKangKang group (DiaoXueKangKang 0.10g / kg) and propranolol propranolol group (propranolol 0. 01g / kg). The rats in each group were administered duodenum 15min after ligation of the coronary artery, and the electrocardiogram of chest multi-lead (9 points) was recorded at different time before and after administration. The myocardial ischemic status And range, coronary artery ligation 3h, remove the heart, with N-BT staining to determine myocardial infarct size. Results: DIA010g / kg decreased ΣST by 24%, 29%, 30% and 27% at 30,60,120 and 180min respectively (P <0.01, P <0.05) NST decreased by 16%, 17%, 16%, 17% (P <0.01 vs control group) for 180 min, and infarct area decreased from 15.14% in the control group to 9.60% (P <0.05 ). Conclusion: Diorexinxuekang can reduce the extent of experimental myocardial ischemia and ischemia in rats, reduce infarct size.