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一、阿斯匹林(乙酰水杨酸) 阿斯匹林是一种最常使用的药物。目前,已经有实验证明了当大剂量的阿斯匹林投给妊娠的实验动物时,则能引起大鼠、小鼠和猴子的先天性畸形。对于孕妇来说,即使是正常剂量也并不安全。芬兰学者研究指出,在妊娠头3个月服用阿斯匹林的母亲生育有缺陷的婴儿比例较高。1975年澳大利亚学者的一次大型研究中,把妊娠中经常服用阿斯匹林的母亲所生的婴儿与未服阿斯匹林所生的婴儿进行了比较,发现前者出生时体重明显降低,婴儿本身血中的阿斯匹林浓度有所增高,而且在分娩前后婴儿的死亡率明显地增加了。同时,因为阿斯匹林能使经常服用者本身发生贫血,故在分娩前后往往会出现阴道流血,或使妊娠期延长,难产比例增
First, aspirin (acetylsalicylic acid) Aspirin is one of the most commonly used drugs. At present, experiments have been conducted to prove that congenital malformations can occur in rats, mice and monkeys when large doses of aspirin are administered to pregnant animals. For pregnant women, even normal doses are not safe. Finnish scholars pointed out that the proportion of infants with defective births in mothers taking aspirin during the first trimester of pregnancy was high. In a large Australian scholar study in 1975, babies born to mothers who took aspirin during pregnancy were compared with infants born without aspirin, and found that the former had a significantly lower birth weight at birth. The baby itself The blood levels of aspirin have increased, and infant mortality has increased significantly before and after childbirth. At the same time, because aspirin can make frequent use of anemia itself, it is often before and after childbirth vaginal bleeding, or to extend the period of pregnancy, dystocia increased by the proportion