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目的研究 Barrett食管（ Barrett’ s Esophagus， BE）在国人内镜下的发病状况和发病特点，并初步探讨其可能的发病机制。方法应用胃镜检查及灌注式食管测压方法研究了 61例 BE与 126例反流性食管炎 (RE)患者在临床表现及食管运动功能方面的区别。结果 BE组与 RE组在各项反流症状上无区别（ P>0.05）；但 BE组合并食管炎的情况少，程度也轻（ P< 0.001）；两组合并消化性溃疡的发生率相似（ P>0.05）； BE组较无并发症的 RE组胃内压力高（ P< 0.05）；其它各项食管测压结果两组无区别（ P>0.05）；结论 BE在中国人中的发病率和发病特点与西方人有不同之处有待于今后更深入系统的研究 ;食管运动功能缺陷可能不是导致中国人群中 RE发展为 BE的主要原因。
Objective To study the incidence and incidence of Barrett’s esophagus (BE) in Chinese under endoscopy and to explore its possible pathogenesis. Methods The difference between clinical manifestations and esophageal motility in 61 patients with BE and 126 patients with reflux esophagitis (RE) was studied by gastroscopy and perfusion esophageal manometry. Results There was no difference between the BE group and the RE group in each symptom of reflux (P> 0.05). However, the BE group combined with esophagitis was less and the degree was also lighter (P <0.001). The incidence of peptic ulcer in both groups was similar (P> 0.05). The intragastric pressure in RE group was higher than that in non-complicated RE group (P <0.05), while the other esophageal manometry results were no significant difference between the two groups (P> 0.05). Conclusion The incidence of BE in Chinese The differences in rates and morbidity characteristics from those in western countries awaited further and systematic studies in the future. Defective esophageal motility may not be the main reason leading to the development of RE in Chinese population.