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This study aims at the theoretical and practical evidence for prevention of restenosis in vitro. Vascular smooth muscle cell (VSMC) model was established using adherent cell culture methods. The proliferation of VSMC was investigated by the cell counting method and 3H-TDR implementation test. The results are as follows. (1) For 125I-seeds, the inhibition rate was 29.3% at 74Bq (p