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目的观察西咪替丁及消旋山莨菪碱治疗儿童过敏性紫癜的临床疗效。方法纳入儿童过敏性紫癜患儿52例,随机分为治疗组和对照组各26例,所有病例均给予抗过敏、抗感染处理等对症治疗,治疗组加用西咪替丁及消旋山莨菪碱治疗,疗程1个月。结果治疗组总有效率92.3%,对照组总有效率84.6%,两组总有效率比较差异有统计学意义(P<0.05)。结论西咪替丁联合消旋山莨菪碱配合基础治疗儿童过敏性紫癜能促进紫癜消失,有益疾病控制。
Objective To observe the clinical efficacy of cimetidine and racemic anisodamine in the treatment of Henoch-Schonlein purpura in children. Methods Fifty-two children with Henoch-Schonlein purpura were randomly divided into treatment group (n = 26) and control group (n = 26). All cases were given anti-allergy and anti-infective treatment. The treatment group was treated with cimetidine Alkali treatment, treatment for 1 month. Results The total effective rate was 92.3% in the treatment group and 84.6% in the control group. There was significant difference between the two groups in the total effective rate (P <0.05). Conclusion Cimetidine combined with racemic anisodamine treatment of children with Henoch-Schonlein purpura can promote the disappearance of purpura, beneficial disease control.