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感染为癌症患者的主要死因。为探索新的抗生素方案,作者用羧噻吩青霉素(Ticarcillin)和磺胺甲基异(口恶)唑-甲氧苄氨嘧啶(SMZ-TMP)联合治疗183例癌症患者的276次发热。发热是指体温高于38.3℃,若微生物学或临床迹象证明为感染者体温低于38.3℃,亦统计在内;不包括因输血液制品或其他已知致热原引起的发热。治疗前均作咽喉、血液、痰和其他损伤灶的细菌培养及 X 线摄片、尿检查等。药物用法:羧噻吩青霉素4g 溶于5%葡萄糖100ml 内,2小时滴完,q.4h(首剂15分钟输注完),SMZ1,200mg 与 TMP240mg 加入375ml 5%葡萄糖
Infection is the leading cause of death in cancer patients. To explore a new antibiotic regimen, the authors combined 276 episodes of fever in 183 cancer patients with ticarcillin and SMZ-TMP. Fever is the body temperature above 38.3 ℃, if the microbiological or clinical evidence of infection is lower than 38.3 ℃ body temperature, also included; does not include blood products or other known pyrogen caused fever. Before treatment were made of throat, blood, sputum and other lesions of the bacterial culture and X-ray, urine examination. Drug Usage: carboxymethyl thiophene penicillin 4g dissolved in 100ml of 5% glucose, drip finished 2 hours, q.4h (the first dose of 15 minutes after infusion), SMZ1, 200mg and TMP240mg added 375ml 5% glucose