Three NE-trending linear structural zones with different strikes are present in the Eastern Subbasin of the South China Sea. They are distributed in the 350-km-wide central region of both sides of the Scarborough seamount chain, representing a morphological indication of the basement faulting. These three zones correspond respectively to three spreading episodes: the magnetic anomalies 6c -6a (24-21 Ma), 6a - 5e (21 - 19 Ma) and 5e - 5d (5c) (19 - 16 Ma). Instability, subsection and asymmetry characterize the seafloor spreading of the subbasin. The spreading directions change in a continuous way in each of the zones, but abrupt changes by 3°-5° occur when crossing the boundary between the zones, reflecting that the spreading direction has evolutionary characteristics of both gradual and sudden changes. NW-trending transform faults of the spreading become progressively densely distributed from the east to the west, cutting the NE-trending zones into several segments, between which the strikes of the NE-trending zones have marked changes. Such features indicate that the spreading axis is associated with subsection along the strike. Around 21 Ma (magnetic anomaly 6a), there was an important event of spreading acceleration, with the full rate rapidly increasing from 30.54 km/Ma to 42.88 km/Ma. This rate increment event corresponds to the sudden changes in the spreading characteristics of basement faulting, sedimentation, volcano activities, etc. The asymmetry of spreading over the eastern part of the Eastern Subbasin is generally larger than that over the western part, and the spreading rate is markedly larger on the southern side than on the northern side. As a result, the oceanic basin is wide in the east and narrow in the west, forming a significantly asymmetric pattern.