论文部分内容阅读
目的探讨尿毒症患者合并膀胱移行细胞癌的临床表现、诊断和治疗方法。方法回顾性分析23例尿毒症患者合并膀胱移行细胞癌的临床资料。长期维持血液透析的患者20例,未行血液透析的患者3例。临床分期:T1期7例,T2期13例,T3期3例。病理分级:Ⅰ级9例,Ⅱ级11例,Ⅲ级3例。均为初发肿瘤。经B超、CT、膀胱镜及病理检查明确诊断。均行手术加膀胱灌注化疗药物治疗。结果至随访截止时间,全组无瘤生存12例,复发15例次,死亡11例,其中非肿瘤致死7例(4例死于心脏病,1例死于血液透析过程中,2例死于脑出血),肿瘤致死4例。肿瘤致死者均为多发、反复发作、高分期和高分级的患者。结论手术加膀胱灌注化疗是尿毒症患者合并膀胱移行细胞癌的主要治疗方法。
Objective To investigate the clinical manifestations, diagnosis and treatment of bladder transitional cell carcinoma in patients with uremia. Methods Retrospective analysis of 23 cases of uremic patients with bladder transitional cell carcinoma of the clinical data. Long-term maintenance of hemodialysis patients 20 cases, 3 cases of hemodialysis patients. Clinical stage: T1 in 7 cases, T2 in 13 cases, T3 in 3 cases. Pathological grading: Ⅰ grade in 9 cases, Ⅱ grade in 11 cases, Ⅲ grade in 3 cases. Are initial tumor. The B-, CT, cystoscopy and pathological examination of a clear diagnosis. All patients underwent surgery and bladder chemotherapy drugs. Results There were 12 patients with tumor-free survival, 15 patients relapsed and 11 patients died. Among them, 7 patients died of non-tumor (4 died of heart disease, 1 died of hemodialysis and 2 died of hemorrhage Intracerebral hemorrhage), tumor death in 4 cases. Tumor deaths are multiple, recurrent, high staging and high grade patients. Conclusions Surgery plus intravesical chemotherapy is the main treatment for uremic patients with bladder transitional cell carcinoma.