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对28例慢性阻塞性肺病患者用复方丹参注射液以漂浮导管直接注入肺动脉内,注射后肺动脉收缩压和舒张压均有明显下降(P<0.001),下降持续时间约5~7分钟;而注生理盐水的对照组,无明显变化(P>0.05),说明丹参确有降低肺动脉压的作用。其中5例在用药前后作肺循环多项动力学指标观察,除肺动脉压降低外,也初步表明与硝苯吡啶有类似的效应。
In 28 chronic obstructive pulmonary disease patients with compound Danshen injection floating catheter directly into the pulmonary artery, pulmonary artery systolic and diastolic blood pressure after injection were significantly decreased (P <0.001), the duration of the decline of about 5 to 7 minutes; and Note Saline control group, no significant change (P> 0.05), indicating that Salvia did reduce pulmonary arterial pressure. Five of them were used for pulmonary circulation before and after treatment for a number of kinetic parameters observed, in addition to reduced pulmonary artery pressure, but also initially showed similar effects with nifedipine.