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[目的]观察苍附导痰汤联合达英-35治疗痰湿型多囊卵巢综合征高雄激素血症疗效。[方法]使用随机平行对照方法,将60例住院患者按病志号抽签法简单随机分为两组。对照组30例达英-35,月经第5d后服用,1片/d,睡前服用,连续21d停药。治疗组30例苍附导痰汤(苍术10g,山药20g,香附10g,茯苓20g,陈皮、法半夏、胆南星各10g,白术、熟地、薏苡仁、菟丝子各20g,当归10g,鹿角胶20g,甘草5g,川芎、枳实各10g),1剂/d,水煎300m L,早晚口服,150m L/次;西药治疗同对照组。连续治疗3个月经周期为1疗程。观测临床症状、多毛评分、痤疮评分、性激素水平、不良反应。连续治疗2疗程,判定疗效。[结果]治疗组痊愈12例,显效11例,有效4例,无效3例,总有效率90.00%。对照组痊愈4例,显效15例,有效1例,无效10例,总有效率66.67%。治疗组疗效优于对照组(P<0.05)。相关指标两组均有改善(P<0.01),治疗组改善优于对照组(P<0.05)。[结论]苍附导痰汤联合达英-35治疗痰湿型多囊卵巢综合征高雄激素血症疗效满意,无严重不良反应,值得推广。
[Objective] To observe the curative effect of Cansifutang Decoction combined with Da Ying-35 on hyperandrogenism of phlegm-damp polycystic ovary syndrome. [Methods] Using randomized parallel control method, 60 inpatients were randomly divided into two groups randomly according to the method of lot drawing. Control group of 30 cases up to Ying-35, menstruation after 5d taking, 1 / d, taking at bedtime, continuous 21d withdrawal. In the treatment group, 30 cases of Cangtousuantan Decoction (Atractylodes 10g, Yam 20g, Cyperus rotundus 10g, Poria 20g, dried tangerine peel, Pinellia tuber, gall bladder austral 10g, Atractylodes, Rehmanniae, Coix seed, 20g, licorice 5g, Chuanxiong, citrus aurantium the 10g), 1 / d, decoction 300m L, morning and evening oral, 150m L / times; Western medicine treatment with the control group. Continuous treatment of 3 menstrual cycle for a course of treatment. Clinical symptoms, hairiness scores, acne scores, sex hormone levels, and adverse reactions were observed. Continuous treatment of 2 courses to determine the efficacy. [Results] The treatment group cured 12 cases, markedly effective in 11 cases, effective in 4 cases, ineffective in 3 cases, the total effective rate was 90.00%. The control group recovered in 4 cases, markedly effective in 15 cases, effective in 1 case, ineffective in 10 cases, the total effective rate was 66.67%. The treatment group was better than the control group (P <0.05). Related indicators improved in both groups (P <0.01), and the treatment group improved better than the control group (P <0.05). [Conclusion] Cansifutan Decoction combined with Darlene-35 is effective in treating hyperandrogenism of phlegm-damp polycystic ovary syndrome without serious adverse reactions and is worth promoting.