舌痛是难治的疾病之一,发病机制复杂。作者从神经元观点研究舌痛的发病机制。患者和方法舌痛患者250例,年龄31～70岁。除常规检查以外,研究交感肾上腺系统和副交感系统的状况,对患者的血液、尿液和唾液进行有关的生化检查;检查颈动脉流域血流图;用毛细血管镜检查舌的微循环状况;测量口腔局部温度;检查舌的味觉和辨别觉。对照组是33名同龄健康人。结果和讨论60%的舌痛患者尿液二羟苯丙氨酸 Tongue pain is one of refractory diseases, the pathogenesis is complex. The author studies the pathogenesis of tongue pain from the viewpoint of neuron. Patients and Methods Tongue pain patients 250 cases, aged 31 to 70 years. In addition to routine examinations, the conditions of the sympathetic adrenal and parasympathetic systems are studied, the biochemical tests are performed on the patient’s blood, urine, and saliva; blood flow maps of the carotid arteries are examined; the microcirculation of the tongue is examined by capillary mirror; Oral local temperature; check tongue taste and discrimination. The control group was 33 healthy people of the same age. Results and Discussion Urinary dihydrophenylalanine in 60% of patients with tongue pain