本实验研究了豚鼠经10Gy γ线照后第三天回肠纵肌和环肌的收缩活动,同时观察其对组织胺的反应。结果表明:照后纵肌收缩幅度增加而频率基本正常,对组织胺的敏感性增强,量效曲线左移,ED_(50)减小;照后环肌出现自发性强收缩,对组织胺的反应性降低。由此认为,照后纵肌和环肌收缩失常和对组织胺反应性改变,可能是引起肠紊乱的部分原因。 In this experiment, the contractile activity of the longitudinal muscle and the circular muscle of the ileum on the third day after guinea pigs were irradiated with 10Gy γ-rays was observed, and the response to histamine was also observed. The results showed that the longitudinal muscle contraction amplitude increased and the frequency was basically normal, the sensitivity to histamine increased, the dose-response curve shifted to the left, ED_ (50) decreased; Reactivity decreased. Therefore, according to the longitudinal muscle and ring muscle contraction and reactivity histamine reaction may be part of the cause of intestinal disorders.