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自Allen发现糖化血红蛋白以来,各实验室不断建立和改进糖化血红蛋白的测定方法并深入研究它和糖尿病控制及慢性并发症间的关系。现已清楚糖化血红蛋白是血红蛋白A组分的某些特殊分子部位和糖经过缓慢而不可逆的非酶促反应结合形成的,它反映
Since Allen’s discovery of HbA1c, laboratories have continuously established and improved assays for HbA1c and in-depth studies on its relationship to diabetes control and chronic complications. It is now clear that glycated hemoglobin is formed by the combination of a slow and irreversible non-enzymatic reaction of certain specialized molecular sites of hemoglobin A component and its reflection