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垂体分泌的生长激素(GH)能促进外周组织合成和分泌胰岛素样生长因子-1(IGF-1),GH的许多生物作用都是通过IGF-1的介导而实现的。然而,过多的IGF-1又可抑制GH的分泌。除此之外,IGF-1的生成又受甲状腺激素(TH)及胰岛素(Ins)的正向调节,垂体GH的分泌,TH也起着重要的作用。TH的生理功能除直接作用于组织器官外,还可通过对GH-IGF-1系统的调节,发挥其生物效应。本文对一组甲状腺功能亢进(甲亢)病人的甲状腺功能(甲功)及GH-IGF-1、Ins的检测,分析它们的变化及其它因素的相关性,从而了解认
Pituitary secreted growth hormone (GH) can promote peripheral tissue synthesis and secretion of insulin-like growth factor-1 (IGF-1), many of the biological effects of GH are mediated through the IGF-1. However, too much IGF-1 can inhibit GH secretion. In addition, IGF-1 production in turn by the thyroid hormone (TH) and insulin (Ins) positive regulation of pituitary GH secretion, TH also plays an important role. In addition to acting directly on tissues and organs, the physiological function of TH can also exert its biological effects through the regulation of the GH-IGF-1 system. This article examines the association between thyroid function (thyroid function) and GH-IGF-1, Ins in a group of patients with hyperthyroidism (hyperthyroidism), analyzes their changes, and other factors