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以玫瑰香精和羟丙基-β-环糊精(HP-β-CD)为原料,采用水浴恒温磁力搅拌法制备玫瑰香精-HP-β-CD包合物;通过L9(34)正交试验对制备工艺进行了优化,并以挥发油包合率和包合产率为指标评价了包合工艺,利用红外(FT-IR)和薄层层析色谱(TLC)对包合物进行了表征。结果表明:HP-β-CD与玫瑰香精形成了包合物,且在包合过程中未改变玫瑰香精的化学成分,提高了玫瑰香精的缓释效果。最佳制备工艺:玫瑰香精1mL,m(HP-β-CD/g)︰V(玫瑰香精/mL)=6︰1,搅拌速度700 r/min,包合温度为50℃,包合时间为5 h。影响因素的大小依次为:包合温度>搅拌速度>玫瑰挥香精和H-β-CDP的投料比>包合时间。
Β-cyclodextrin (HP-β-CD) was used as the raw material to prepare the rose essence-HP-β-CD inclusion complex by a magnetic stirrer in water bath. The preparation process was optimized. The inclusion process of volatile oil inclusion rate and inclusion yield was evaluated. The inclusion complex was characterized by FT-IR and TLC. The results showed that HP-β-CD formed an inclusion complex with rose essence, and did not change the chemical composition of rose essence during the inclusion process, thereby improving the sustained-release effect of rose essence. The optimal preparation conditions were as follows: 1mL of rose essence, m (HP-β-CD / g): V (rose essence / mL) = 6︰1, stirring speed 700 r / min, inclusion temperature of 50 ℃ 5 h. The influencing factors were as follows: inclusion temperature> stirring speed> the ratio of rosin flavoring to H-β-CDP> inclusion time.