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心脏再同步化治疗( CRT)是难治性心力衰竭的有效治疗方法。其可以改善基线QRS波时限( QRSd)>0.15 s心力衰竭患者的临床症状,降低心血管事件发生率。然而,其在基线QRSd <0.15 s合并心室机械收缩不同步的心力衰竭人群中的应用价值尚未完全明确。 CRT治疗的有效性与基线QRSd相关,基线QRSd可能是CRT治疗反应性的重要预测因素。现就目前心力衰竭的CRT治疗研究进展、基线QRSd与CRT治疗反应性的关系等方面做一综述。“,”Cardiac resynchronization therapy( CRT) is an effective therapy in patients with refractory heart failure.It can effectively improve the clinical symptoms of heart failure patients with baseline QRS duration >150 ms, and reduce the incidence of cardiovascular e-vents.However, its applied value in heart failure patients with baseline QRS duration 120~150 ms,and concurrent involvement of ventricu-lar mechanical dyssynchrony is not yet entirely clear.This indicates that the effectiveness of CRT is associated with the baseline QRS dura-tion.This article provides a summary of the current treatment progress of CRT in heart failure patients, and the relationship between baseline QRS duration and the response of CRT in those patients.