Studies addressing the type-specific outcomes of cervical human papillomavirus (HPV) infections in women started emerging since the early 2000s, resulting in prolific literature and more profound understanding of the dynamic nature of these viral outcomes (incident infections, persistence and clearance) in the female genital tract.1,2 Despite the fact that scattered studies on genital HPV infections in males have been published since the late 1980s,3 interest in these lesions has been meager, and studies published until now have failed to provide any information about the natural history of male genital HPV infections at the genotype level.